| 发明名称 | Sublingual films | ||
| 摘要 | The invention features sublingual film formulations of dopamine agonists and methods of treating Parkinson's disease, tremors, restless leg syndrome, sexual dysfunction, and depressive disorders therewith. | ||
| 申请公布号 | US9283219(B2) | 申请公布日期 | 2016.03.15 |
| 申请号 | US201414478975 | 申请日期 | 2014.09.05 |
| 申请人 | Cynapsus Therapeutics, Inc. | 发明人 | Bryson Nathan John;Giovinazzo Anthony John;Barnhart Scott David;Koons Michael Clinton |
| 分类号 | A61K31/4045;A61K31/506;A61K31/4985;A61K9/70;A61K31/473;A61K31/4415;A61F13/00;A61K47/02;A61K9/00;A61K47/14;A61K47/38;A61K31/485;A61K45/06;A61K31/381;A61K31/428;A61K31/48;A61K9/24 | 主分类号 | A61K31/4045 |
| 代理机构 | Clark & Elbing LLP | 代理人 | Bieker-Brady Kristina;Clark & Elbing LLP |
| 主权项 | 1. A pharmaceutical composition in unit dosage form formulated for sublingual administration, wherein said unit dosage form is a film comprising a first portion comprising apomorphine hydrochloride and a second portion comprising from 10±2 to 50±5% (w/w) of a pH neutralizing agent that is an organic base having a pKa of 5±2, wherein said unit dosage form comprises from 2 to 60 mg of apomorphine hydrochloride. | ||
| 地址 | Toronto CA | ||