NOVEL 6-TRIAZOLOPYRIDAZINE SULPHANYL BENZOTHIAZOLE AND BENZIMIDAZOLE DERIVATIVES, PROCESS FOR PREPARING SAME, USE THEREOF AS MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS AND NOVEL USE ESPECIALLY AS MET INHIBITORS

摘要

The invention relates to the novel products of formula (I): in which ---- represents a single or double bond; Ra represents H, Hal, alkoxy, O-cycloalkyl, heteroaryl, phenyl, NHCOalk, NHCOcycloalk or NR1R2; X represents S, SO or SO2; A represents NH or S; W represents H, alkyl or COR with R representing cycloalkyl; alkyl optionally substituted with NR3R4, alkoxy, hydroxyl, phenyl, heteroaryl or heterocycloalkyl; alkoxy optionally substituted with NR3R4, i.e. an O-(CH2)n-NR3R4 radical, an O-phenyl radical or an O-(CH2)n-phenyl radical, with phenyl optionally substituted and n= 1 to 4; or the NR1R2 radical; R1 represents H or alk and R2 represents H, cycloalkyl or alkyl; R3 and R4 represent H, alk, cycloalkyl, heteroaryl or phenyl; R1, R2 and/or R3, R4 form, with N, a ring optionally containing O, S, N and/or NH; all heterocycloalkyls, heteroaryls, phenyls and cyclic groups being optionally substituted; these products being in any of the isomer forms and the salts, as medicaments, especially as MET inhibitors