Carotid body ablation via directed energy

摘要

Methods and devices for assessing, and treating patients having sympathetically mediated disease, involving augmented peripheral chemoreflex and heightened sympathetic tone by reducing chemosensor input to the nervous system via carotid body ablation.

主权项

1. A method of carotid septum ablation to treat at least one of heart failure and hypertension, comprising endovascularly positioning a distal region of a catheter within an internal jugular vein or one of its tributaries and proximate a carotid septum, the distal region comprising an ultrasound ablation transducer;
targeting carotid septum tissue for ablation with ablative ultrasound energy without targeting a carotid sinus by rotating the ultrasound ablation transducer within the jugular vein to aim the ablative ultrasound energy towards the carotid septum tissue and away from the carotid sinus; and directing the ultrasound ablation energy towards the carotid septum and away from the carotid sinus to ablate the carotid septum tissue with ablative ultrasound energy, to treat at least one of heart failure and hypertension.