发明名称 |
composto, composição farmacêutica, e, uso de um composto. |
摘要 |
Compound of formula I are antagonists of the PGD2 receptor, CRTH2, and as such are useful in the treatment and/or prevention of CRTH2-mediated diseases such as asthma in combination with a second active ingredient such as a leukotriene antagonist. |
申请公布号 |
BRPI1008906(A2) |
申请公布日期 |
2016.03.15 |
申请号 |
BR2010PI08906 |
申请日期 |
2010.02.19 |
申请人 |
MERCK CANADA INC.;MERCK SHARP & DOHME CORP. |
发明人 |
CARL BERTHELETTE;JOEY METHOT;JOHN COLUCCI;KARINE VILLENEUVE;MICHAEL BOYD |
分类号 |
A61K31/405;A61K31/4192;A61K31/435;A61P11/06;C07D403/04;C07D471/04 |
主分类号 |
A61K31/405 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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