发明名称 |
CATALYTIC WITTIG AND MITSUNOBU REACTIONS |
摘要 |
A catalytic Wittig method utilizing a phosphine including the steps of providing a phosphine oxide precatalyst and reducing the phosphine oxide precatalyst to produce the phosphine; forming a phosphonium ylide precursor from the phosphine and a reactant; generating a phosphonium ylide from the phosphonium ylide precursor; reacting the phosphonium ylide precursor with the aldehyde, ketone, or ester to form the olefin and the phosphine oxide which then reenters the cycle. The invention is also directed to a Mitsunobu reaction catalytic in phosphine. |
申请公布号 |
EP2417082(B1) |
申请公布日期 |
2016.03.16 |
申请号 |
EP20100762310 |
申请日期 |
2010.04.06 |
申请人 |
THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM |
发明人 |
O'BRIEN, CHRISTOPHER, J. |
分类号 |
C07B37/04;C07C1/34;C07C15/52;C07C17/263;C07C22/08;C07C45/72;C07C49/796;C07C67/343;C07C69/52;C07C69/618;C07C69/65;C07C69/75;C07C69/76;C07C201/12;C07C205/57;C07C253/30;C07C255/01;C07D333/24;C07D333/28 |
主分类号 |
C07B37/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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