| 发明名称 |
USE OF 1H-INDAZOLE-3-CARBOXAMIDE COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 BETA INHIBITORS |
| 摘要 |
1H-indazole-3-carboxamide compounds as glycogen synthase kinase 3 beta inhibitors. The present invention relates to the 1H-indazole-3-carboxamide compounds for use as glycogen synthase kinase 3 beta (GSK-3&bgr;) inhibitors and to their use in the treatment of GSK-3&bgr;-related disorders such as, for example, (i) insulin-resistance disorders; (ii) neurodegenerative diseases; (iii) mood disorders; (iv) schizophrenic disorders; (v) cancerous disorders; (vi) inflammation, (vii) substance abuse disorders; and (viii) epilepsies. |
| 申请公布号 |
PT2817301(E) |
申请公布日期 |
2016.03.14 |
| 申请号 |
PT20130703799T |
申请日期 |
2013.02.08 |
| 申请人 |
AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO - A.C.R.A.F. - S.P.A. |
发明人 |
BARBARA GAROFALO;MARIA ALESSANDRA ALISI;NICOLA CAZZOLLA;GUIDO FURLOTTI;GABRIELE MAGARO';ROSELLA OMBRATO;FRANCESCA MANCINI |
| 分类号 |
C07D401/12;A61K31/454;A61K31/4545;A61P3/00;A61P25/00;A61P29/00;A61P35/00;C07D401/14;C07D405/14;C07D413/14;C07D417/14 |
主分类号 |
C07D401/12 |
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