发明名称 NOVEL BENZAZEPINE DERIVATIVE AND PHARMACEUTICAL USE THEREOF
摘要 An object of the present invention is to provide a compound having a V2 receptor agonistic activity. Provided is a pharmaceutical composition which contains, as an active ingredient, a compound represented by the general formula (I) described below: [wherein R 1 is the formula described below: (wherein A is a lower alkylene group which may be substituted with a lower alkyl group, or the like; R 6 is a hydrogen atom, or the like; R 7 is a hydroxyl group, an aromatic heterocyclic group which may be substituted with a lower alkyl group, a carbamoyl group, or the like) ; R 2 is a hydrogen atom or a lower alkyl group; R 3 is a lower alkyl group which may be substituted with 1 to 3 fluorine atoms, or a halogen atom; R 4 is a five-membered aromatic monocyclic heterocyclic group, a five-membered non-aromatic monocyclic heterocyclic group, or the like, (provided that each of these heterocyclic groups contains at least one nitrogen atom and may be substituted with a lower alkyl group) ; and R 5 is a lower alkyl group, a halogen atom, or the like], or a pharmacologically acceptable salt thereof.
申请公布号 HK1208676(A1) 申请公布日期 2016.03.11
申请号 HK20150109366 申请日期 2015.09.24
申请人 SANWA KAGAKU KENKYUSHO CO. LTD. 发明人 KATSUNORI KITAMOTO;NOBUYOSHI KASUGAI;HIROYO KATAOKA;YASUSHI OHSAWA;YUKA KUNO;HIROKI FUJIEDA;KEITA SAKAI;HIROKI NAGANO;NAOKI TAKAHASHI;TORU IZUCHI;MITSUAKI TAKEUCHI;DAISUKE KURUMAZUKA;TOSHIYUKI MIYAZAWA;SATOKO HARADA;IZUMI GOTOH;YUKIYASU ASANO;YURIE YAMADA;MORIO OKABE
分类号 C07D;A61K;A61P 主分类号 C07D
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