发明名称 Compuesto de amidina o sal del mismo
摘要 The purpose of the present invention is to provide a novel compound which has an anti-fungal activity on pathogenic fungi including fungi belonging to the genus Candida, the genus Aspergillus and the genus Trichophyton and is useful as a medicinal agent. A compound represented by formula (I) (wherein A 1 represents a nitrogen atom or a group represented by formula CR 6 ; A 2 and A 3 are the same as or different from each other and independently represent a nitrogen atom or a group represented by formula CH; R 1 represents an aryl group which may be substituted by 1 to 5 substituents independently selected from a substituent group (2) or the like; R 2 and R 3 are the same as or different from each other and independently represent a hydrogen atom, a halogen atom, a C 1-6 alkyl group, a C 1-6 haloalkyl group or a C 1-6 alkoxy group; and R 4 and R 5 are the same as or different from each other and independently represent a hydrogen atom, a C 1-6 haloalkyl group, a C 1-6 alkyl group or the like) or a salt thereof is useful as an anti-fungal agent.
申请公布号 ES2563232(T3) 申请公布日期 2016.03.11
申请号 ES20120819674T 申请日期 2012.07.27
申请人 Taisho Pharmaceutical Co., Ltd.;Toyama Chemical Co., Ltd. 发明人 TANIKAWA, Tetsuya;USHIKI, Yasunobu;USHIYAMA, Fumihito;YAMAGUCHI, Toru;ONO, Naoya;YAMAMOTO, Keiko;TSURUTA, Risa;TSUTSUI, Yasuhiro;FUJINO, Noritomo;MORI, Ayumu
分类号 C07D277/28;A61K31/426;A61K31/427;A61K31/433;A61K31/4439;A61K31/454;A61K31/496;A61K31/497;A61K31/501;A61K31/506;A61K31/5377;A61P17/00;A61P31/10;C07D277/20;C07D277/30;C07D277/34;C07D277/48;C07D277/56;C07D285/08;C07D417/04;C07D417/12 主分类号 C07D277/28
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