发明名称 |
A COMPOSITION COMPRISING THE COMPOUNDS(ID-56D1B) ISOLATED FROM AN EXTRACT OF IXERIS DENTATA NAKAI FOR TREATING OR PREVENTING XEROSTOMIA |
摘要 |
The present invention relates to a composition for preventing and treating xerostama, containing a compound isolated from an Ixeris dentata (Thunb.) Nakai. extract as an active ingredient. According to the present invention, the Ixeris dentata (Thunb.) Nakai. extract promotes amylase secretion when co-treating high-concentration glucose and Ixeris dentata (Thunb.) Nakai. together, in an experiment using human salivary gland (HSG) cells, and decreases expression of proteins associated with endoplasmic reticulum stress. In addition, an oxidation-reduction environment in an endoplasmic reticulum associated with protein synthesis is well maintained after short-term and long-term co-treatment of high-concentration glucose. Thus, the composition of the present invention can be useful as a pharmaceutical composition for preventing and treating xerostama and a functional health food. |
申请公布号 |
KR20160028422(A) |
申请公布日期 |
2016.03.11 |
申请号 |
KR20160011329 |
申请日期 |
2016.01.29 |
申请人 |
INDUSTRIAL COOPERATION FOUNDATION CHONBUK NATIONAL UNIVERSITY |
发明人 |
CHAE, HAN JUNG;KIM, HYUNG RYONG;KIM, SEUNG HYUN |
分类号 |
A61K31/7048;A61K31/365;A61K36/28 |
主分类号 |
A61K31/7048 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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