发明名称 EYE-REFRESHING AGENT TO ELIMINATE AND ALLEVIATE EYE FATIGUE AND DISCOMFORT
摘要 An eye-refreshing agent, the raw materials of which include mung bean germs, eucalyptus leaves, mint leaves, clove leaves, camphor leaves and borneol. The plant cells thereof are respectively subjected to crushing, low-temperature freezing and centrifugation and sound membrane separation to prepare a water-soluble preparation. The preparation can prevent and alleviate visual fatigue and accelerate metabolism of the eye skin cells, and also has the effect of alleviating and improving eye bags and eye pseudo-wrinkles caused by eye fatigue.
申请公布号 US2016067297(A1) 申请公布日期 2016.03.10
申请号 US201414783203 申请日期 2014.02.21
申请人 WEI Jianxue 发明人 Wei Jianxue
分类号 A61K36/61;A61K36/54;A61K36/534;A61K31/045;A61K36/48 主分类号 A61K36/61
代理机构 代理人
主权项 1. An eye-refreshing agent for eliminating and alleviating eye fatigue and discomfort, characterized in that the eye-refreshing agent is an eye skin external-use care agent which is prepared from mung bean germ, eucalyptus leaves, clove leaves, mint leaves, camphor, and borneol as raw materials and in form of spraying agent, ointment, eye patch or aqueous agent, and the eye-refreshing agent is prepared from following components, parts by weight, as effective pharmaceutical components: sound-membrane separation extract of mung bean germ 10 to 80, sound-membrane separation extract of eucalyptus leaves 10 to 80, sound-membrane separation extract of mint leaves 5 to 50, sound-membrane separation extract of clove leaves 5 to 50, sound-membrane separation extract of camphor leaves 1 to 10, borneol 0.1 to 1, the method for preparing the eye-refreshing agent comprises the following steps: preparing the sound-membrane separation extract of mung bean germ, which includes: cutting fresh mung bean germs coarsely and then mixing with water of 0.3 to 0.5 times by weight; placing mixed solution into a ultrasonic cell crusher to crush into cell slurry; performing a centrifugation treatment on the cell slurry through a centrifuge; taking out supernatant and then separating the supernatant through a sound membrane separator, thereby obtaining the sound membrane separation extract of mung bean germ, having a molecular weight of less than 6000 D; preparing the sound-membrane separation extract of eucalyptus leaves, which includes: breaking mechanically fresh eucalyptus leaves and then adding water of 0.5 to 0.6 times by weight and mixing; placing mixed solution into an ultrasonic cell crusher to crush into cell slurry; performing a centrifugation treatment on the cell slurry through a centrifuge; taking out supernatant and then separating the supernatant through a sound membrane separator, thereby obtaining the sound membrane separation extract of eucalyptus leaves, having a molecular weight of less than 6000 D; preparing the sound-membrane separation extract of mint leaves, which includes: breaking mechanically fresh mint leaves, and then adding water of 0.5 to 0.6 times by weight and mixing; placing mixed solution into an ultrasonic cell crusher to crush into cell slurry; performing a centrifugation treatment on the cell slurry through a centrifuge; taking out supernatant and separating the supernatant through a sound membrane separator, thereby obtaining the sound-membrane separation extract of mint leaves, having a molecular weight of less than 6000 D; preparing the sound-membrane separation extract of clove leaves, which includes: breaking mechanically fresh clove leaves, and then adding water of 0.5 to 0.6 times by weight and mixing; placing mixed solution into an ultrasonic cell crusher to crush into cell slurry; performing a centrifugation treatment on the cell slurry through a centrifuge; taking out supernatant and separating the supernatant through a sound membrane separator, thereby obtaining the sound-membrane separation extract of clove leaves, having a molecular weight of less than 6000 D; preparing the sound-membrane separation extract of camphor leaves, which includes: breaking mechanically fresh camphor leaves, and then adding water of 0.5 to 0.6 times by weight and mixing; placing mixed solution into an ultrasonic cell crusher to crush into cell slurry; performing a centrifugation treatment on the cell slurry through a centrifuge; taking out supernatant and separating the supernatant through a sound membrane separator, so as to obtain the sound-membrane separation extract of camphor leaves, having a molecular weight of less than 6000 D; mixing the above sound membrane separation extracts and formulating them according to the parts by weight as defined above, and then performing a frozen centrifugation on them at a centrifugal rotation speed of 3000 rpm˜4000 rpm for 10 to 20 minutes at a temperature in range of 0˜4° C., to remove sediments; separating centrifugation solution again through a sound membrane separator, so as to obtain mixed sound-membrane separation extract having a molecular weight of less than 6000 D; mixing with borneol the mixed sound-membrane separation extract obtained after the mixing and separation, to prepare spraying agent, ointment, eye patch or aqueous agent according to a preparation process for spraying agent, ointment, eye patch or aqueous agent.
地址 Xi'an City, Shaanxi CN