| 摘要 |
FIELD: medicine.SUBSTANCE: invention refers to medicine and pharmaceutical industry and concerns composition and method of producing the preparation of highly effective pharmaceutical substance and excipients allowing to form a fine particle aerosol to penetrate into the bronchi and pulmonary alveoli. Inhalation formulation for treating bronchial asthma and chronic obstructive pulmonary disease, containing as active component fenoterol hydrobromide, as a solvent-pure ethyl alcohol, a propellant, the propellant contains HFA-134a and/or HFA-227ea, as well as additionally contains an acidity regulator selected from hydrochloric acid, phosphoric and citric acids, as a substance which regulates the distribution profile, triethyl citrate.EFFECT: invention provides higher respirable fraction up to 35-40 % and obtaining optimum distribution profile of particles.2 cl, 1 dwg, 4 ex |
