发明名称 |
METHODS AND BIOCOMPATIBLE COMPOSITIONS TO ACHIEVE SUSTAINED DRUG RELEASE IN THE EYE |
摘要 |
A nanostructured biocompatible wafer for placement in the conjunctival cul-de-sac. The wafer contains a tissue-reactive mucoadhesive polymer and a mesh formed of a plurality of hydrophobic polymer fibers. Also provided is a method for treating glaucoma, an ocular surface disorder, or an ocular surface infection using the nanostructured biocompatible wafer. Additionally, an injectable sustained-release formulation for treating an ocular disorder is disclosed. The formulation includes a drug contained within a plurality of microparticles formed of a biodegradable polymer and are coated with a tissue-reactive compound. Further provided is a method for treating an ocular disorder by injecting the microparticulate sustained release formulation. |
申请公布号 |
CA2960213(A1) |
申请公布日期 |
2016.03.10 |
申请号 |
CA20152960213 |
申请日期 |
2015.09.08 |
申请人 |
INTEGRAL BIOSYSTEMS LLC |
发明人 |
BARMAN, SHIKHA P.;LIU, MOLI;BARMAN, KOUSHIK;WARD, KEVIN L.;HACKETT, BRENDAN |
分类号 |
A61F2/00 |
主分类号 |
A61F2/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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