发明名称 |
BIORESORBABLE WOUND DRESSING |
摘要 |
FIELD: medicine.SUBSTANCE: invention represents a non-woven fabric applicable for GDF-5 protein delivery and containing the fibres of a fibrous raw material comprising bioresorbable and/or biocompatible polymers; these fibres contain GDF-5 protein including a cystine-knot domain with an amino acid identity of at least 60% to 102 aa-cystine-knot domain of human GDF-5 relevant to amino acids 400-501 SEQ ID NO: 2. The above GDF-5 protein is distributed in the fibres. The invention also refers to the wound dressing, wound pad and implant that contain the above non-woven fabric.EFFECT: higher efficacy.17 cl, 9 dwg, 4 ex |
申请公布号 |
RU2577155(C2) |
申请公布日期 |
2016.03.10 |
申请号 |
RU20140101762 |
申请日期 |
2012.06.21 |
申请人 |
BIOFARM GEZELLSHAFT TSUR BIOTEKHNOLOGISHEN ENTVIKLUNG FON FARMAKA MBKH;KARL FROJDENBERG KG |
发明人 |
PLEGER, FRANK;REBEL, DENI;GRAFAREND, DIRK;NOJMJULLER, DANIEL |
分类号 |
A61K9/70;A61K38/18;A61L15/22;A61L15/32;A61P41/00 |
主分类号 |
A61K9/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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