发明名称 A METHOD FOR GENERATING INDUCED PLURIPOTENT STEM CELLS
摘要 The invention relates to a method for generating induced pluripotent stem cells, wherein the method comprises: step a) of inducing non-pluripotent cells to produce a mixture comprising induced pluripotent stem cells and non-pluripotent cells; step b) of contacting the mixture comprising induced pluripotent stem cells and non-pluripotent cells obtainable from step a) with a binding agent, wherein the binding agent is capable of binding an epitope consisting of the non-reducing terminal saccharide structure according to formula (Fucα1-2)aGalβ1-3HexNAcβ, wherein a=0 or 1 and Hex is either Glc or Gal; and step c) of selecting an induced pluripotent stem cell bound by the binding agent.
申请公布号 US2016068818(A1) 申请公布日期 2016.03.10
申请号 US201414785020 申请日期 2014.04.16
申请人 Glykos Finland Oy 发明人 MIKKOLA Milla;OTONKOSKI Timo;Mononen Heli;SATOMAA Tero;SAARINEN Juhani
分类号 C12N5/074;G01N33/569 主分类号 C12N5/074
代理机构 代理人
主权项
地址 Helsinki FI