Electrochemical-based analytical test strip with ultra-thin discontinuous metal layer

摘要

An electrochemical-based analytical test strip for the determination of an analyte (such as glucose) in a bodily fluid sample includes an electrically insulating base layer, a first electrically conductive layer disposed on the electrically insulating base layer and including at least one electrode, an enzymatic reagent layer disposed on the at least one electrode, a patterned spacer layer and a top layer. The electrochemical-based analytical test strip also includes an ultra-thin discontinuous metal layer with a nominal thickness of less than 10 nanometers disposed between the first electrically conductive layer and the top layer. Moreover, at least the patterned spacer layer defines a sample-receiving chamber containing the at least one electrode, and the ultra-thin discontinuous metal layer is disposed at least within the sample-receiving chamber.