发明名称 ANTI-IL-4/ANTI-IL-13 BISPECIFIC ANTIBODY FORMULATIONS
摘要 The present invention provides stable pharmaceutical antibody formulations, including lyophilized formulations, comprising an anti-IL-4/anti-IL-13 bispecific antibody and a buffering system, wherein the pH of the formulation is about pH 7, and wherein the formulation has a low salt concentration in order to reduce the ionic strength of the formulation. The formulations may, optionally, further comprise a non-ionic surfactant, a sugar, and/or a non-ionic stabilizing agent. The formulations can be used in the treatment of various diseases.
申请公布号 EP2991678(A1) 申请公布日期 2016.03.09
申请号 EP20140724659 申请日期 2014.04.29
申请人 SANOFI 发明人 CARAYON, SOPHIE;BOUSSIF, OTMANE
分类号 A61K39/395;C07K16/24 主分类号 A61K39/395
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