发明名称 |
METHOD AND KIT FOR PURIFYING NUCLEIC ACIDS |
摘要 |
Methods for automated extraction of nucleic acids are disclosed. Also disclosed are method and kits for isolating fetal nucleic acids from a plasma sample of a pregnant woman. The method includes flowing the plasma sample through a first filter under conditions that allow binding of the fetal and maternal nucleic acids to the first filter; eluting the fetal and maternal nucleic acids bound to the first filter to produce a concentrated nucleic acid sample; flowing the concentrated nucleic acid sample through a second filter under conditions that allow preferential binding of the maternal nucleic acids to the second filter; and recovering the fetal nucleic acid from the concentrated nucleic acid sample that flow through the second filter. |
申请公布号 |
EP2890966(A4) |
申请公布日期 |
2016.03.09 |
申请号 |
EP20130832099 |
申请日期 |
2013.08.27 |
申请人 |
AKONNI BIOSYSTEMS, INC. |
发明人 |
HOLMBERG, REBECCA;GINDLESPERGER, ALISSA, ERIN;STOKES, TINSLEY, JANNA;BELGRADER, PHILLIP |
分类号 |
G01N1/34;C12Q1/68;G01N33/48 |
主分类号 |
G01N1/34 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|