发明名称 グルタチオンアルキルエステル同位体置換体および反応性代謝物の検出方法
摘要 [Problem] To provide a novel isotope-labeled compound that can be used as a trapping agent and that is useful for picking out drug-candidate compounds that produce reactive metabolites. [Solution] Provided is a glutathione alkylester isotopologue represented by general formula (1). In formula (1), R1 represents a linear or branched alkoxy group in which at least one of carbon, oxygen, and hydrogen atoms contained therein is isotope-labeled and which has 1 to 8 carbon atoms or a cycloalkoxy group in which at least one of carbon, oxygen, and hydrogen atoms contained therein is isotope-labeled and which has 3 to 8 carbon atoms.
申请公布号 JP5878170(B2) 申请公布日期 2016.03.09
申请号 JP20130516202 申请日期 2012.05.21
申请人 杏林製薬株式会社 发明人 山岡 俊和
分类号 C07K5/037;C07B59/00;G01N27/62 主分类号 C07K5/037
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