Power generating and control apparatus for the treatment of tissue

摘要

Apparatus, systems, and methods are provided for the generation and control of energy delivery in a dosage to elicit a therapeutic response in diseased tissue. A balloon catheter can have electrodes attached to a power generator and controller such that the balloon and electrodes contact tissue during energy treatment. Energy selectively may be applied to tissue based on measured impedance to achieve gentle heating. Calibration of the apparatus and identification of attached accessories by computing the circuit impedance prior to energy dosage facilitate regulation of power delivery about a set point. Energy delivery can be controlled to achieve substantially uniform bulk tissue temperature distribution. Energy delivery may beneficially affect nerve activity.

主权项

1. A power generating apparatus for treatment of tissue having a circuit comprising:
a direct digital synthesizer (DDS) operatively coupled to a power amplifier; a power output set point controller providing a signal; a peak effective power sensor receiving voltage and current feedback measured during delivery of power from the circuit to a power delivery target, the peak effective power sensor providing a signal based on the feedback; and a PID controller, operatively coupled to receive the signals from the power output set point controller and the peak effective power sensor, and operatively coupled to direct a modulating voltage signal to the power amplifier such that output of power from the circuit is maintained within a range about a power output set point in response to the signal from the peak effective power sensor, wherein the output of power from the circuit is continuously maintained during a treatment period, wherein the power amplifier is comprised of a variable gain amplifier and a linear power amplifier operatively coupled in series.