主权项 |
1. A method for achieving an effect in a patient comprising the administration of a therapeutically effective amount of a compound having structural Formula I or a pharmaceutically acceptable salt or ester thereof, wherein:
R1 is chosen from hydrogen, aryl, alkyl, arylalkyl, heteroaryl, heteroarylalkyl, and CONR10R11, any of which may be optionally substituted.R2 is chosen from aryl and heteroaryl, either of which may be optionally substituted; and R10 and R11 are each independently chosen from hydrogen, lower alkyl, aryl, or optionally, R10 and R11 can be taken together to form a heterocycloalkyl, or heteroaryl; to a patient, wherein the effect is selected from the group consisting of reduction of triglycerides, reduction of cholesterol, and reduction of hemoglobin Alc. |