发明名称 |
Method for producing 3,5-dimethyldodecanoic acid; and 4-carboxy-3,5-Dimethyl-3,5-dodecadienoic acid |
摘要 |
Provided is a process for producing 3,5-dimethyldodecanoic acid, which is an active ingredient of the pheromone of California prionus, and 4-carboxy-3,5-dimethyl-3,5-dodecadienoic acid which is an intermediate useful for producing 3,5-dimethyldodecanoic acid. More specifically, provided is a method for producing 3,5-dimethyldodecanoic acid, comprising the steps of subjecting 3-methyl-2-pentene-1,5-diacid diester (1) and 2-nonanone (2) to a condensation reaction and subsequent hydrolysis into 4-carboxy-3,5-dimethyl-3,5-dodecadienoic acid (3); decarboxylating or decarboxylating and hydrolyzing the 4-carboxy-3,5-dimethyl-3,5-dodecadienoic acid (3) into 3,5-dimethyl-2,4-dodecadienoic acid (4); and hydrogenating the 3,5-dimethyl-2,4-dodecadienoic acid (4) into 3,5-dimethyldodecanoic acid (5), as shown in the following scheme:; |
申请公布号 |
US9278899(B2) |
申请公布日期 |
2016.03.08 |
申请号 |
US201514713582 |
申请日期 |
2015.05.15 |
申请人 |
Shin-Etsu Chemical Co., Ltd. |
发明人 |
Baba Akihiro;Kinsho Takeshi;Ishibashi Naoki |
分类号 |
C07C51/36;C07C51/373;C07C51/09;C07C51/38;C07C57/13 |
主分类号 |
C07C51/36 |
代理机构 |
Myers Bigel Sibley & Sajovec |
代理人 |
Myers Bigel Sibley & Sajovec |
主权项 |
1. A method for producing 3,5-dimethyldodecanoic acid, comprising the steps of:
subjecting 3-methyl-2-pentene-1,5-diacid diester (1): wherein R1 and R2 may be the same or different and each represents a monovalent hydrocarbon group having from 1 to 5 carbon atoms, and 2-nonanone (2):to a condensation reaction and subsequent hydrolysis to obtain 4-carboxy-3,5-dimethyl-3,5-dodecadienoic acid (3): decarboxylating or decarboxylating and hydrolyzing the 4-carboxy-3,5-dimethyl-3,5-dodecadienoic acid (3) into 3,5-dimethyl-2,4-dodecadienoic acid (4):and
hydrogenating the 3,5-dimethyl-2,4-dodecadienoic acid (4) into 3,5-dimethyldodecanoic acid (5): |
地址 |
JP |