发明名称 錠剤の製造方法及び錠剤
摘要 The object of the present invention is to provide a tablet manufacturing method and also to provide a tablet such as a carbonated spring bathing liquid in which although an aqueous solution after dissolution of the tablet becomes neutral in pH, neutralization reactions are allowed to take place efficiently and intensively inside the tablet, bubbles of carbon dioxide gas which are small in size as much as possible are continuously generated for a certain period of time, thereby the thus generated carbon dioxide gas is mostly dissolved in water without escaping into the air to increase concentrations of total carbonate components in water, and carbon dioxide gas in contact with the skin is designed to be easily converted to bicarbonate ions due to a pH value of the aqueous solution thereof and, therefore, absorbed through the skin, and this subject is solved by a tablet manufacturing method for conducting compression molding in the presence of an organic acid in a range of 1:10 to 1:3 and polyethylene glycol in a range of 1:100 to 1:5 in relation to bicarbonate (sodium hydrogen carbonate or potassium hydrogen carbonate), in which the tablet is subjected to compression molding so that an aqueous solution after dissolution of the tablet is from 5.5 to 8.5 in pH and the tablet is 15kg or more in hardness and the tablet is also 7mm or more both in diameter and thickness.
申请公布号 JP5877778(B2) 申请公布日期 2016.03.08
申请号 JP20120229900 申请日期 2012.10.17
申请人 株式会社ホットアルバム炭酸泉タブレット 发明人 小星重冶;吉本博
分类号 A61K8/19;A61K8/36;A61K8/365;A61K8/44;A61K8/46;A61K8/86;A61Q19/10 主分类号 A61K8/19
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