| 发明名称 |
SYNTHESIS OF BACE INHIBITORS. |
| 摘要 |
The present invention provides a one step carbonylation of a compound of formula II in the presence of water to afford a compound of formula (I), useful in processes to manufacture BACE inhibitors. |
| 申请公布号 |
MX2015014728(A) |
申请公布日期 |
2016.03.07 |
| 申请号 |
MX20150014728 |
申请日期 |
2014.04.23 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
MICHELANGELO SCALONE;ALEC FETTES;HANS-PETER MARTY |
| 分类号 |
C07D213/79;C07D213/803;C07D213/85;C07D241/24;C07D413/12 |
主分类号 |
C07D213/79 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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