发明名称 |
PARTICLE SIZE REDUCTION OF AN ANTIMUSCARINIC COMPOUND. |
摘要 |
The present invention relates to a process for preparing a crystalline micronised particulate of a glycopyrronium salt. The process involves suspending the drug in a water immiscible anti-solvent in which the drug has little or no solubility and micronizing the suspension. The resulting drug particles are physically stable with regard to agglomeration and/or aggregation on storage. |
申请公布号 |
MX2015014904(A) |
申请公布日期 |
2016.03.07 |
申请号 |
MX20150014904 |
申请日期 |
2014.04.24 |
申请人 |
CHIESI FARMACEUTICI S.P.A. |
发明人 |
IRENE PASQUALI;ANDREA CASAZZA;MARK SAUNDERS;ELENA LOSI |
分类号 |
A61K9/00;A61K9/14 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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