Una línea de proceso para la producción de partículas liofilizadas

摘要

The invention relates to the general field of freeze-drying of, for example, pharmaceuticals and other high-valued goods. According to one embodiment of the invention, a freeze-dryer for the bulkware production of freeze-dried particles under closed conditions comprises a rotary drum (302) for receiving the frozen particles; and a stationary vacuum chamber (202) housing the rotary drum (302). For the production of the particles under closed conditions the vacuum chamber (202) is adapted for closed operation during at least part of a production run, and the drum (302) is in open communication with the vacuum chamber (202).