| 发明名称 |
SURFACTANT MICROBUBBLES AND PROCESS FOR PREPARING AND METHODS OF USING THE SAME |
| 摘要 |
The invention relates to an ultrasound contrast agent (UCA) comprising an outer shell and a gas core. The gas core is filled with oxygen, and the outer shell comprises a first surfactant and a second surfactant. The invention also relates to a method of making an oxygen-filled UCA and delivering oxygen to a local area of a subject's body. The method comprises injecting a composition comprising an oxygen-filled UCA of the invention into the subject's body; directing ultrasound radiation to the local area in an intensity sufficient to rupture the UCA. |
| 申请公布号 |
US2016059036(A1) |
申请公布日期 |
2016.03.03 |
| 申请号 |
US201514835636 |
申请日期 |
2015.08.25 |
| 申请人 |
Drexel University ;Thomas Jefferson University |
发明人 |
Eisenbrey John Robert;Wheatley Margaret Alison;O'Kane Patrick;Albala Lorenzo;Forsberg Flemming |
| 分类号 |
A61N5/10;A61K9/50;A61K41/00;A61K49/22 |
主分类号 |
A61N5/10 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An ultrasound contrast agent (UCA) comprising an outer shell and a gas core, wherein said gas core is filled with substantially pure oxygen, and
wherein said outer shell comprises a first surfactant and a second surfactant. |
| 地址 |
Philadelphia PA US |
