NEUROPROTECTIVE GANODERMA COMPOSITIONS AND METHODS OF USING THE SAME

摘要

PROBLEM TO BE SOLVED: To provide methods for treatment of degenerative neurological disorders such as Parkinson's disease and Alzheimer's disease by inhibiting activation of microglial cells overactivated in response to neuronal damage.SOLUTION: Methods for treatment of degenerative neurological disorders comprise administering, to a subject in need of such treatment, an effective amount of a Ganoderma lucidum extract. The Ganoderma lucidum extract is obtained from the fruiting body of Ganoderma lucidum by low temperature extraction.EFFECT: Ganoderma lucidum extract attenuates inflammatory responses of microglial cells to exogenous or endogenous stimulus and/or protect against degeneration of dopaminergic neurons, allowing the use in treatment of degenerative neurological disorders.SELECTED DRAWING: None