发明名称 COMPOUNDS FOR THEIR USE AS DRUGS FOR THE TREATMENT AND/OR THE PREVENTION OF INFECTION(S) CAUSED BY BIOFILM-FORMING BACTERIA
摘要 The present invention relates to compounds of the following formula (I), wherein: m represents an integer being equal to 0, 1, 2, 3, 4, 5 or 6, X represents a simple bond or a radical -CHR1 wherein R1 represents: - a hydrogen atom, or - a linear or branched, possibly interrupted by up to 3 heteroatoms selected from O, S or N and/or possibly substituted, (C1-C12)-alkyl, R2, R3 and R4 represent independently from each other: - a hydrogen atom, or - a linear or branched (C1-C12-alkyl or (C1-C12)-acyl R5 represents: - a hydrogen atom, or - a linear or branched, possibly substituted, (C1-C13)-alkyi possibly substituted and possibly interrupted by up to 3 heteroatoms selected from O, S or N, R6 represents: - a hydrogen atom, or - a linear or branched possibly substituted (C1-C12)-alkyl, possibly substituted and possibly interrupted by up to 3 heteroatoms selected from O, S or N, for their use as antibacterial drugs for the treatment and/or the prevention of infection(s) caused by biofilm-forming bacteria.
申请公布号 WO2016030434(A1) 申请公布日期 2016.03.03
申请号 WO2015EP69571 申请日期 2015.08.26
申请人 CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE;UNIVERSITE D'ORLEANS;JAGIELLONIAN UNIVERSITY 发明人 MARTIN, OLIVIER;GALLIENNE-BOIVINEAU, ESTELLE;NICOLAS, CYRIL;HECZKO, PIOTR B.;STOCHEL, GRAZYNA;STRUS, MAGDALENA;KYZIOL, AGNIESZKA;MIKOLAJCZYK, DIANA;MACHUL, AGNIESZKA
分类号 C07D471/04;A61K31/40;A61K31/435;A61P31/04;C07D207/12;C07D211/46 主分类号 C07D471/04
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