SYSTEM AND METHOD FOR ABLATING A TISSUE SITE BY ELECTROPORATION WITH REAL-TIME PULSE MONITORING

摘要

A medical system for ablating a tissue site by electroporation with real-time pulse monitoring during an electroporation treatment procedure is provided. The treatment control module monitors applied pulses and detect an abnormal condition that indicates either an ineffective electroporation of the tissue or an imminent excessive current such as a spark event that may exceed the capacity of the pulse generator. Rather than terminating the procedure entirety, the treatment control module temporarily pauses the procedure to allow the user to adjust the pulse parameters so as to complete the procedure without starting the procedure over again.

主权项

1. A medical system for ablating a tissue site by electroporation with real-time pulse monitoring during an electroporation treatment procedure, comprising:
at least two electrodes adapted to be introduced near a target region of a tissue site of a patient; a pulse generator configured to generate and apply between the electrodes a plurality of electroporation pulses according to selected pulse parameters for ablation of tissue in the target region; a treatment control module adapted to detect an abnormal condition of the applied electrical pulses in real-time during an electroporation treatment procedure and temporarily pause the procedure without termination when the abnormal condition is detected, the abnormal condition indicating that a predetermined current threshold value is about to be exceeded or indicating an ineffective electroporation of the tissue.