摘要 |
The present invention provides nucleic acids encoding transcription factors and methods of using these nucleic acids to modulate nicotine production in plants and to produce plants having modulated nicotine production. Nicotine is found predominantly in the genus Nicotiana and in low quantities in some other species ofthe family Solanaceae (Sheen SJ (1988) J Food Science 53: 1572-1573). Nicotine is the most abundant alkaloid in commercial tobacco (N. tabacum L.) cultivars (Siminszky et al. (2005) Proc Nat! Acad Sci US A 102: 14919-14924), and naturally plays an 25 important role in tobacco resistance to insect herbivores (Steppuhn et al (2004) PLoS Biology 2:1074-1080). |