PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING OVARY GRANULOSA CELL TUMORS CONTAINING GLYCOGEN SYNTHASE KINASE-3 BETA INHIBITOR AS ACTIVE INGREDIENT, AND FUNCTIONAL HEALTH FOOD COMPOSITION

摘要

A pharmaceutical composition for preventing or treating ovary granulosa cell tumors containing, as an active ingredient, one selected from the group consisting of a compound represented by chemical formula 1, a pharmaceutically acceptable salt of the compound represented by chemical formula 1, a compound represented by chemical formula 2, and a pharmaceutically acceptable salt of the compound represented by chemical formula 2, or a functional health food composition. The composition inhibits glycogen synthase kinase-3 beta (GSK3beta) and thus has an effect of inhibiting a phosphorylation of a serine, which is the 33rd amino acid of the forkhead box L2 (FOXL2) protein.

主权项

1. A pharmaceutical composition for preventing or treating a granulosa cell tumor of the ovary, comprising:
one selected from the group consisting of a compound represented by Formula 1, a pharmaceutically acceptable salt of the compound represented by Formula 1, a compound represented by Formula 2, and a pharmaceutically acceptable salt of the compound represented by Formula 2, as an active ingredient.