发明名称 DRUG FOR PREVENTING AND/OR TREATING POLYCYSTIC KIDNEY DISEASE
摘要 An object of the present invention is to provide a combination drug that has remarkably excellent preventive and/or therapeutic effects on polycystic kidney disease. The present invention provides a drug for preventing and/or treating polycystic kidney disease comprising a combination of tolvaptan or a prodrug thereof with a somatostatin derivative, and a method for treating polycystic kidney disease using this drug.
申请公布号 US2016058841(A1) 申请公布日期 2016.03.03
申请号 US201514935592 申请日期 2015.11.09
申请人 OTSUKA PHARMACEUTICAL CO., LTD. 发明人 FUJIKI Hiroyuki;AIHARA Miki;KINOSHITA Shizuo
分类号 A61K38/31;A61K31/55;A61K9/00 主分类号 A61K38/31
代理机构 代理人
主权项 1. A method of manufacturing a drug for preventing and/or treating polycystic kidney disease, the method comprising the steps of: providing tolvaptan or a prodrug thereof; providing a somatostatin derivative; and preparing a drug which is a combination of tolvaptan or a prodrug thereof with a somatostatin derivative, in the form of either: a single formulation (a mixture) comprising tolvaptan or a prodrug thereof with a somatostatin derivative, or separate formulations (concomitants), one of the formulations comprising tolvaptan or a salt thereof, and the other comprising a somatostatin derivative.
地址 Tokyo JP