Therapy and Prevention of Problem Drinking

摘要

The present invention provides methods for the therapy and prevention of problem drinking in alcohol-dependent and non-dependent subjects and those at risk of developing problem drinking behavior, and compositions of matter comprising oxytocin or an analog or derivative thereof or an agonist or partial agonist of an oxytocin receptor that are useful in preventing or treating problem drinking.

主权项

1. A method of treatment or prophylaxis of problem drinking, said method comprising administering to a subject an amount of a composition comprising oxytocin or an analog or derivative thereof or an oxytocin receptor agonist for a time and under conditions sufficient to reduce alcohol consumption by the subject to a level that constitutes moderate drinking behavior or abstinence from alcohol, or to inhibit or prevent alcohol consumption by the subject, thereby treating or preventing problem drinking in the subject.