CHITOSAN-BASED HEMOSTATIC TEXTILE

摘要

A microfibrillar high molecular weight chitosan-based textile can be used as a hemostat. The chitosan has been treated in a nitrogen field by applying energy to ionize nitrogen in and around the chitosan textile. A single or multiple such treatments may be employed. For example, the chitosan textile may be irradiated under nitrogen using γ-irradiation, treated under a nitrogen plasma, or both.

主权项

1. A method of making a hemostatic textile material, comprising processing crab shells to obtain a high molecular weight chitosan having a molecular weight in a range about 600-800 kDa and a degree of deacetylation of about 75-88%, processing the high molecular weight chitosan into a textile comprising a network of chitosan fibers, and irradiating the high molecular weight chitosan textile under nitrogen using γ-irradiation.