METHODS AND COMPOSITIONS RELATED TO PROSTATE CANCER THERAPEUTICS
摘要
Disclosed herein are compositions and methods for detecting biological molecules and biomarkers associated with prostate cancer. Disclosed herein are compositions and methods for detecting biological molecules and biomarkers associated with castration- resistant prostate cancer wherein such biological molecules and biomarkers comprise androgen-receptor splice variants that can be used to develop effective therapeutic regimens for prostate cancer patients. Disclosed herein are methods of using biological molecules and biomarkers related to androgen-receptor splice variants for assessing therapeutic resistance to drugs such as enzalutamide and abiraterone.
申请公布号
CA2959336(A1)
申请公布日期
2016.03.03
申请号
CA20152959336
申请日期
2015.08.25
申请人
THE JOHNS HOPKINS UNIVERSITY
发明人
LUO, JUN;ANTONARAKIS, EMMANUEL S.;LU, CHANGXUE;ISAACS, WILLIAM