发明名称 MODULATION OF ANGIOPOIETIN-LIKE 3 EXPRESSION
摘要 Provided herein are methods, compounds, and compositions for reducing expression of an ANGPTL3 mRNA and protein in an animal. Also provided herein are methods, compounds, and compositions for reducing plasma lipids, plasma glucose and atherosclerotic plaques in an animal. Such methods, compounds, and compositions are useful to treat, prevent, delay, or ameliorate any one or more of cardiovascular disease or metabolic disease, or a symptom thereof.
申请公布号 US2016060626(A1) 申请公布日期 2016.03.03
申请号 US201514821982 申请日期 2015.08.10
申请人 ISIS PHARMACEUTICALS, INC. 发明人 Crooke Rosanne M.;Graham Mark J.;Lee Richard;Dobie Kenneth W.
分类号 C12N15/113;C12Q1/68 主分类号 C12N15/113
代理机构 代理人
主权项
地址 Carlsbad CA US