发明名称 |
Pharmaceutical composition for treatment and/or prevention of cancer |
摘要 |
The objective of the present invention is to provide an antibody that targets CAPRIN-1 and that exhibits antitumor activity superior to that of conventional antibodies, and an application for said antibody as a therapeutic agent and/or preventative agent for cancer. The present invention provides an antibody that targets CAPRIN-1 polypeptides that are specifically expressed on the surface of cancer cells, and an application for the antibody as a therapeutic agent and/or preventative agent for cancer. Provided are an antibody that is immunologically reactive with CAPRIN1-protein and a fragment of said antibody, the antibody containing a heavy chain region including the complementarity determining regions of SEQ ID Nos. 1, 2 and 3, and a light chain region including the complementarity determining regions of SEQ ID Nos. 4, 5 and 6. Further provided is a pharmaceutical composition for the treatment and/or prevention of cancer and having the antibody or fragment as an active ingredient thereof. |
申请公布号 |
AU2014303375(A1) |
申请公布日期 |
2016.03.03 |
申请号 |
AU20140303375 |
申请日期 |
2014.08.08 |
申请人 |
TORAY INDUSTRIES, INC. |
发明人 |
OKANO, FUMIYOSHI;SAITO, TAKANORI;MINAMIDA, YOSHITAKA;IDO, TAKAYOSHI |
分类号 |
C07K16/18;A61K39/395;A61K45/00;A61P35/00;A61P35/02;C07K16/46;C12N15/09;C12P21/08 |
主分类号 |
C07K16/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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