Synthetic scFv analogue to the 6313/G2 (anti angiotensin II type 1 receptor) monoclonal antibody variable regions

摘要

SYNTHETIC scFv ANALOGUE TO THE 6313/G2 (ANTI ANGIOTENSIN II TYPE 1 RECEPTOR) MONOCLONAL ANTIBODY VARIABLE REGIONS The present invention provides a specific binding molecule comprising a polypeptide having an amino acid sequence as shown in Figure 16 herein, or a sequence at least 95% identical thereto. The present invention also provides a specific binding molecule comprising a polypeptide encoded by a polynucleotide sequence as shown 10 in Figure 16 herein, or a sequence at least 95% identical thereto. The present invention also provides the use of such a specific binding molecule in the treatment of cancer.