BIODEGRADABLE NETWORK POLYMERS FOR REGENERATIVE MEDICINE AND TISSUE ENGINEERING

摘要

The disclosure relates to biodegradable polyether network polymers crosslinked via ester linkages, to substrates, implants and scaffolds comprising the biodegradable polyether network polymers, to methods for preparing such network polymers, implants and scaffolds, and to methods of using substrates, implants and scaffolds comprising the network polymers, particularly for culturing cells and regenerating tissue.

主权项

1. A biodegradable polyether network polymer crosslinked via ester linkages which is prepared by polymerising a monomer composition comprising a multifunctional polyether monomer and a multifunctional crosslinking monomer, wherein one of the polyether monomer and the crosslinking monomer comprises a hydroxy functional group and the other of the polyether monomer and the crosslinking monomer comprises a complementary functional group capable of reacting with the hydroxy functional group to form an ester linkage, and wherein at least one selected from the polyether monomer and the crosslinking monomer is branched.