| 摘要 |
An anticancer agent comprising a compound represented by the formula (I) [R 1 represents hydrogen atom, hydroxyl group, a C 1-6 alkoxy group and the like; R 2 and R 3 represents hydrogen atom, a halogen atom, a C 1-6 alkyl group and the like; R 4 represents hydrogen atom, a C 1-6 alkyl group, a C 1-6 alkylsulfonyl group and the like; R 5 represents hydrogen atom or a substituent; .... represents a single bond or a double bond; R 6 and R 7 represents hydrogen atom, a C 1-6 alkyl group and the like; R 8 represents hydrogen atom, a C 1-6 alkyl group and the like; A represents -O-, -S-, or - CH 2 -; D represents -C= or -N=; X represents methylene group, -O-, or -CO-; Q represents -N= or -C(R 8 )=; and Y represents a heterocyclic group or amino group], which shows a superior inhibitory activity against pim-1 kinase. |
