发明名称 |
METHOD FOR DRUG LOADING HYDROXYAPATITE COATED IMPLANT SURFACES |
摘要 |
A method for loading a hydroxyapatite coated implant with a therapeutic agent including the steps of providing an implant and applying a hydroxyapatite coating on a surface of the implant. The hydroxyapatite coated implant is contacted with a solution including the therapeutic agent. The hydroxyapatite coated implant and solution is heated to temperature of about 60° C. to about 100° C. Pressure is applied to the hydroxyapatite coated implant and solution from about 2 bar to about 10 bar, to load the hydroxyapatite coated implant with the therapeutic agent. An implant made ac cording to the method has sustained therapeutic agent delivery and includes a base and a biomimetic hydroxyapatite coating disposed on a surface thereof. |
申请公布号 |
EP2988793(A1) |
申请公布日期 |
2016.03.02 |
申请号 |
EP20140723131 |
申请日期 |
2014.04.22 |
申请人 |
STRYKER TRAUMA GMBH |
发明人 |
LILJA, MIRJAM;SÖRENSEN, JAN HENRIK;PROCTER, PHILIP;STECKEL, HARTWIG;SÖRENSEN, TORBEN |
分类号 |
A61L27/54;A61C8/00;A61L27/32 |
主分类号 |
A61L27/54 |
代理机构 |
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