METHODS FOR OBTAINING RETINAL PROGENITORS, RETINAL PIGMENTED EPITHELIAL CELLS AND NEURAL RETINAL CELLS

摘要

The present invention pertains to a method for in vitro obtaining human retinal progenitors, comprising the steps of (i) placing an adherent culture of human pluripotent stem cells in a pro-neural medium; and (ii) maintaining this culture in said pro-neural medium until the appearance of pigmented cells and/or of neuroepithelial-like structures. Advantageously, additional steps can be performed to obtain RPE cells and/or precursors of the neural retina.