System and method for gross anatomic pathology using hyperspectral imaging

摘要

A method for analyzing organ samples using hyperspectral imaging comprising illuminating an organ sample to generate interacted photons, collecting the interacted photons and passing the interacted photons through a tunable filter. The filtered interacted photons are detected to generate a hyperspectral image. A brightfield image is generated and associated with the hyperspectral image. Spectra from locations of interest are extracted and analyzed to assess a characteristic of the organ sample. A system may comprise an illumination source to illuminate an organ sample and generate interacted photons, a collection optics for collecting the interacted photons and a tunable filter to filter the interacted photons. A detector is configured to detect the filtered photons and generate at least one hyperspectral image. The detector may also be configured to generate at least one brightfield image representative of the organ sample.

主权项

1. A method of analyzing a biological organ, the method comprising:
illuminating the biological organ to generate a first plurality of interacted photons; collecting the first plurality of interacted photons to generate a first optical signal; separating the first optical signal into a plurality of orthogonally polarized optical components; filtering the plurality of optical components into a plurality of passband wavelengths to generate a plurality of filtered photons; detecting the plurality of filtered photons to generate at least one hyperspectral image; and analyzing the at least one hyperspectral image by extracting a spectrum from a location in the at least one hyperspectral image, wherein the location corresponds to an area of interest of the biological organ, and analyzing the extracted spectrum to identify a characteristic of the biological organ.