发明名称 Cell scaffold constructs
摘要 The present invention relates to the regeneration, reconstruction, repair, augmentation or replacement of organs or tissue structures using scaffolds and autologous cells that are not derived from such organs or tissues.
申请公布号 US9271824(B2) 申请公布日期 2016.03.01
申请号 US201213682614 申请日期 2012.11.20
申请人 REGENMEDTX, LLC 发明人 Ludlow John W.;Jayo Manuel J.;Basu Joydeep;Bertram Timothy A.;Genheimer Christopher W.;Guthrie Kelly I.;Ilagan Roger M.;Jain Deepak;Knight Oluwatoyin A.;Payne Richard;Quinlan Sarah F.;Rapoport H. Scott;Sangha Namrata D.
分类号 A61F2/04;A61M27/00;A61L27/18;A61L27/38 主分类号 A61F2/04
代理机构 Arnold & Porter LLP 代理人 DeVry Christopher;Arnold & Porter LLP
主权项 1. An implantable construct for replacement of a defective bladder in a human subject comprising a) a tubular scaffold having a first open end configured for anastomosis to an opening in the subject's abdominal wall, a second open end configured to connect to a ureter; and b) an autologous cell population that is not derived from the defective bladder, deposited on or in a surface of the tubular scaffold, wherein the cell population is a smooth muscle cell population derived from adipose tissue or peripheral blood, and wherein the implantable construct is adapted for temporary storage and passage of urine.
地址 Winston-Salem NC US