| 发明名称 | Methods for treating combined radiation and thermal injury | ||
| 摘要 | The present invention provides methods for treating a subject that has suffered combined exposure to total body ionizing irradiation and burns by administering a peptide of at least 5 amino acids of a peptide of SEQ ID NO:1 (Asp-Arg-Nle-Tyr-Ile-His-Pro), or a pharmaceutical salt thereof in an amount effective to treat the radiation effects and/or the burn. | ||
| 申请公布号 | US9272013(B2) | 申请公布日期 | 2016.03.01 |
| 申请号 | US201113637038 | 申请日期 | 2011.03.28 |
| 申请人 | University of Southern California | 发明人 | Rodgers Kathleen E.;diZerega Gere S. |
| 分类号 | A61K38/08 | 主分类号 | A61K38/08 |
| 代理机构 | McDonnell Boehnen Hulbert & Berghoff LLP | 代理人 | McDonnell Boehnen Hulbert & Berghoff LLP |
| 主权项 | 1. A method for improving survival in a subject that has suffered combined (i) exposure to total body ionizing irradiation of at least 0.2 Gy, and (ii) second degree burns over at least 7% of the subject's total body surface area, comprising administering to the subject an amount effective to treat the radiation effects and the burn of a peptide consisting of the peptide of SEQ ID NO:1 (Asp-Arg-Nle-Tyr-Ile-His-Pro), or a pharmaceutical salt thereof, wherein the method improves survival in the subject compared to control. | ||
| 地址 | Los Angeles CA US | ||