Pyrrolo[2,3-D]pyrimidine compounds

摘要

Described herein is pyrrolo{2,3-d}pyrimidine compounds, their use as Janus Kinase (JAK) inhibitors, pharmaceutical compositions containing this compounds, and methods for the preparation of these compounds.

主权项

1. A method for treating an autoimmune disease or disorder selected from autoimmune thrombocytopenia, autoimmune hemolytic anemia, systemic lupus erythematosus, and bullous pemphigoid in a mammal comprising administering to a mammal in need thereof a therapeutically effective amount of a compound of formula I:or a pharmaceutically acceptable salt thereof wherein R1 is C1-4alkyl optionally substituted with hydroxy.