| 发明名称 | Method of producing microcapsules | ||
| 摘要 | A method of producing microcapsules of the type having a core and a coating encapsulating the core comprises the steps of providing a core-forming fluid stream and a coating-forming fluid stream, providing a two spray nozzle arrangement having a core nozzle disposed concentrically about a second nozzle, spraying the core-forming fluid stream from the core nozzle and the coat-forming fluid stream from the concentric nozzle to produce microcapsules, and solidifying the microcapsules upon formation in a suitable gas. Spray drying or spray chilling may be employed as the means of solidifying the microcapsules. Microcapsules having a core and a solid coat are also described. | ||
| 申请公布号 | US9271942(B2) | 申请公布日期 | 2016.03.01 |
| 申请号 | US200712513390 | 申请日期 | 2007.11.07 |
| 申请人 | ROYAL COLLEGE OF SURGEONS IN IRELAND | 发明人 | Ramtoola Zebunnissa |
| 分类号 | A61K9/50 | 主分类号 | A61K9/50 |
| 代理机构 | Nixon Peabody LLP | 代理人 | Nixon Peabody LLP |
| 主权项 | 1. A method of producing microcapsules by spray-drying, the microcapsules having a D50% of less than 125 μm, and a core and a coating encapsulating the core, the method comprising the steps of providing a core-forming fluid stream and a coating-forming liquid stream, providing a two spray nozzle arrangement having a tip with an outer nozzle disposed concentrically about a core nozzle, spraying the core-forming fluid stream from the core nozzle and the coating-forming liquid stream from the outer nozzle to produce atomised droplets, and drying the droplets in a heated gas to produce the microcapsules. | ||
| 地址 | Dublin IE | ||