发明名称 Sanglifehrin derivatives and methods for their production
摘要 There are provided inter alia compounds of formula (I) and (II); and their use in therapy, particularly for the treatment of viral infection.
申请公布号 US9271977(B2) 申请公布日期 2016.03.01
申请号 US201113995666 申请日期 2011.12.20
申请人 NeuroVive Pharmaceutical AB 发明人 Moss Steven James;Gregory Matthew Alan;Wilkinson Barrie;Kendrew Steven Gary;Martin Christine Janet
分类号 A61K31/5025;C07D491/107;A61P31/18;A61P31/14;A61K31/501;A61K45/06 主分类号 A61K31/5025
代理机构 Dann, Dorfman, Herrell & Skillman 代理人 Netter, Jr. Robert C.;Dann, Dorfman, Herrell & Skillman
主权项 1. A compound selected from: which can also be represented as which can also be represented as: including any tautomer thereof; or an isomer thereof in which the C26, 27 C═C bond shown as trans is cis; and including a methanol adduct thereof in which a ketal is formed by the combination of the C-53 keto and the C-15 hydroxyl group and methanol; or a pharmaceutically acceptable salt thereof.
地址 Lund SE