| 发明名称 | Levothyroxine formulation with acacia | ||
| 摘要 | A pharmaceutical composition comprising thyroxine, acacia, and an antioxidant selected from propyl gallate, butylated hydroxyanisol, and butylated hydroxytoluene is disclosed. The pharmaceutical composition has an improved shelf life. In one embodiment, the composition additionally comprises sucrose, microcrystalline cellulose, and mannitol. The pharmaceutical composition may be used for treating thyroid disorders by orally administering the composition to a patient in need thereof. | ||
| 申请公布号 | US9271951(B2) | 申请公布日期 | 2016.03.01 |
| 申请号 | US201213723485 | 申请日期 | 2012.12.21 |
| 申请人 | Mylan Inc. | 发明人 | Kirsch John;Nallamothu Ramakrishna;Polat Baris E. |
| 分类号 | A61K31/198;A61K31/235;A61K36/48;A61K9/20 | 主分类号 | A61K31/198 |
| 代理机构 | Frost Brown Todd LLC | 代理人 | Frost Brown Todd LLC |
| 主权项 | 1. A pharmaceutical composition comprising thyroxine, acacia, and about 0.001% wt % to about 0.5% wt % of an antioxidant selected from propyl gallate, butylated hydroxyanisol, and butylated hydroxytoluene, and wherein the composition comprises from about 0.1% wt % to about 10% wt % acacia. | ||
| 地址 | Canonsburg PA US | ||