BIOLOGICAL MARKERS USEFUL IN CANCER IMMUNOTHERAPY

摘要

Methods are disclosed that are based on the finding that serum and plasma levels of eotaxin, MIP1a, and CRP act as important biomarkers that are useful for determining the feasibility in instigating immunotherapeutic treatment of cancer when immunizing with the GV1001 peptide (EARPALLTSRLRFIPK; derived from human telomerase protein), optionally when combined with state of the art combination treatment with Gemcitabine and Capecitabine. In particular, the present invention provides methods for determining whether patients should be treated GV1001 and for determining whether instigated treatment should be continued.